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Foshan Jiazhinuo Biotechnology Co.,Ltd
Foshan Jiazhinuo Biotechnology Co.,Ltd

China Pramipexole CAS 104632-26-0 Mirapex for Treating Parkinson manufacturer

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Pramipexole CAS 104632-26-0 Mirapex for Treating Parkinson 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;Bitcoin 
Place of Origin: Guangdong, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: 25kg/Drum
Production Capacity: 1000kg/month
Delivery Date: 4days

CBNumber: CB0486178
Molecular formula: C10H17N3S
Molecular weight: 211.33
MOL File: 104632-26-0.mol
Chemical properties of pramipexole

CAS: 104632-26-0

English name: Pramipexole

Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole Pramipexole (USAN) Pramipexole free base; Pramipexole alkaline; PRAMIPEXOLE 2HCL MONOHYDRATE; Pramipexol diclorohidrato monohidrato (SAN-

Chinese name: Pramipexole

Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole; Pramipexole and intermediates; Pramipexole Hydrochloride D5; Pramipexole (standard)

CBNumber: CB0486178

Molecular formula: C10H17N3S

Molecular weight: 211.33

MOL File: 104632-26-0.mol

Chemical properties of pramipexole

Melting point: 288-290 ° C

Storage conditions: -20 ° C Freezer

CAS database: 104632-26-0 (CAS DataBase Reference)


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Properties, Application and Production Process 


Chemical properties

Pramipexole Dihydrochloride: C10H17N3S? 2HCl. [104632-25-9]. Crystallization from methanol, m.p. 296-298 ° C. [?] D20> -67.2 (c = 1, methanol).


Uses


Dopamine D2 receptor antagonist. For the treatment of Parkinson's disease.


production method 


Diamino-4,5,6,7-tetrahydrobenzothiazole was dissolved in 34 ml of DMF, 0.022 mol of n-propanal was added and heated at 50 ° C for 1 h. After cooling, 0.02 mol of   was added and the mixture was heated at 50 ° C for 30 min. Most of the solvent was evaporated under reduced pressure and the residue was dissolved in 20 ml of water and adjusted to pH 1 with 2 mol / L hydrochloric  . The aqueous layer was extracted with ethyl acetate, and the extract and organic layer discarded. Potassium carbonate was added to the aqueous layer to basicity, then extracted with ethyl acetate. The extract was dried, concentrated and a solution of HCl in ether was added to give pramipexole dihydrochloride in 42% yield, m.p. 286-288C.


Ms. Karry
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Tel: 86-0757-82035343
Mobile: 86- 188 2631 2629
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Company Info

Foshan Jiazhinuo Biotechnology Co.,Ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Foshan
Province/State: Guangdong
Country/Region: China (Mainland)

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