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Foshan Jiazhinuo Biotechnology Co.,Ltd
Foshan Jiazhinuo Biotechnology Co.,Ltd

China Pharma Inhibitors Powder GSK2118436 / Dabrafenib CAS 1195765-45-7 for Anticancer manufacturer

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Pharma Inhibitors Powder GSK2118436 / Dabrafenib CAS 1195765-45-7 for Anticancer 

Price: 1.0 USD 
Payment Terms: T/T,WU,Money Gram;Bitcoin 
Place of Origin: Guangdong, China (Mainland) 
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Product Detail

Model No.: 13690838732
Production Capacity: 1000kg/month
Delivery Date: 4days
Brand: Nanjian
Cas: 1195765-45-7
Means of Transport: Ocean,Land,Air
Packing: 25kg/Drum
Assay: 99%
apperance: White powder

CAS NO: 1195765-45-7
MF: C23H20F3N5O2S2
MW: 519.5624096
EINECS: 200-366-3
Appearance: White to slightly yellowish-white crystalline
Assay: 99%min

Dabrafenib Profile


Product name: Dabrafenib 

Synonyms: Dabrafenib;N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(tert-butyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;Dabrafenib free base(GSK2118436A);Dabrafenib(GSK2118436);GSK2118436A;Dabrafenib (GSK2118436);Dabrafenib KB-57246;Debrafenib API

CAS NO: 1195765-45-7

MF: C23H20F3N5O2S2

MW: 519.5624096

EINECS: 200-366-3

Appearance: White to slightly yellowish-white crystalline

Assay: 99%min

Storage: Shading, confined preservation


Pharma Inhibitors Powder GSK2118436 / Dabrafenib CAS 1195765-45-7 for Anticancer


Product Name: Dabrafenib (GSK2118436)
Synonyms: Dabrafenib;N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(tert-butyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;Dabrafenib free base(GSK2118436A);Dabrafenib (GSK2118436);GSK2118436A;Dabrafenib (GSK2118436A);Dabrafenib KB-57246;Debrafenib API
CAS: 1195765-45-7
MF: C23H20F3N5O2S2
MW: 519.5624096


Dabrafenib Description:


Dabrafenib (trade name Tafinlar, GSK2118436) is a drug for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth. Dabrafenib has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.[1][2]

The Food and Drug Administration initially approved dabrafenib as a single agent treatment for patients with BRAF V600E mutation-positive advanced melanoma on May 30, 2013.[3] Clinical trial data demonstrated that resistance to dabrafinib and other BRAF inhibitors occurs within 6 to 7 months.[4] To overcome this resistance, the BRAF inhibitor dabrafenib was combined with the MEK inhibitor trametinib.[4] On January 8, 2014, the FDA approved this combination of dabrafenib and trametinib for BRAF V600E/K-mutant metastatic melanoma.


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Company Info

Foshan Jiazhinuo Biotechnology Co.,Ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Foshan
Province/State: Guangdong
Country/Region: China (Mainland)

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