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Foshan Jiazhinuo Biotechnology Co.,Ltd
Foshan Jiazhinuo Biotechnology Co.,Ltd

China Levobupivacaine Hydrochloride rINN 27262-48-2 Liposuction Local Anaesthetic Drug manufacturer

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Levobupivacaine Hydrochloride rINN 27262-48-2 Liposuction Local Anaesthetic Drug 

Price: 1.0 USD 
Payment Terms: T/T,WU,Paypal,Money Gram 
Place of Origin: Hubei, China (Mainland) 
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Product Detail

Means of Transport: Ocean,Land,Air
Packing: as your requst
Assay: 98%
package: as your request
Appearance: yellow to yellow-green liqu...
Production Capacity: 5000kg
Delivery Date: after payment 3-7days
MOQ: 10GRAMS
Payment: T/T
CAS: 431-03-8

Product Name: Levobupivacaine hydrochloride
CAS: 27262-48-2
MW : 324.8887
MF: C13H20N2O3S.HCl
EINECS:245-957-7

 

What is Levobupivacaine Hydrochloride?


Levobupivacaine Hydrochloride is the hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property.


Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.


Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AbbVie under the trade name Chirocaine.


Quick Details


Product NameLevobupivacaine hydrochloride
CAS27262-48-2
MFC18H29ClN2O
MW324.89
Purity99%
Appearancewhite crystalline powder
UsageLocal anaesthetics
CategoriesPharmaceutical Raw Materials;Active Pharmaceutical Ingredients;API;Inhibitors
SynonymsTIMTEC-BB SBB001337;(S)-(-)-BUPIVACAINE HCL;
(S)-(-)-BUPIVACAINE HYDROCHLORIDE;
(S)-(-)-1-N-BUTYL-2',6'-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE; (S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE; s-(-)-1-butyl-2',6'-pipecoloxylidide hydrochloride; (s)-1-butyl-2',6'-piperidinecarboxamidemonohydrochloride; (s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride


Description


Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.


The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation and transmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia. In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.






Application


Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.

The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.

Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.


Dosage and Usage


Indications are mainly used for surgical epidural anesthesia.Adult for nerve block or infiltration anesthesia, a maximum dose of 150mg. Concentration of the preparation of the solution: surgical epidural block: 0.5% ~ 0.75% 10 ~ 20ml 50 ~ 150mg moderate to all motor block.

COA


Product NameLevobupivacaine hydrochloride
Batch .15061201Mfg. date2016.06.12
Approval Date2016.06.23Exp. date2018.06.01
DescriptionWhite Or Almost White Crystalline PowderDate of Expiry2017.12.01
Results Of Analysis Tests
TestAnalysis StandardResults
Melting Point139~145ºC139.5~142.5ºC
Specific Rotation+55°~ +58°+57.2°
Loss On Drying0.32%≤1.0%
Residue On Ignition0.03%≤0.2%
Assay99.36%98.0%~101.0%
ConclusionBe Conform With Enterprise Standard
Molecular formula


Competitive advantages


1. Rich experience


Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our steroide and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.

2. Great quality and high purity


Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure
our client's need. Welcome order the samples, MOQ just 10 grams.

3. Safest and fastest delivery


We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Trackingnumber would be informed quickly after shipment.
We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.

4. Good after-sales service


24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!

5. Experiential shopping
Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make.


Ms. Karry
skype Ms. Karry
Sales Manager
Tel: 86-188-26312629
Fax: 86-0757-82035343
Mobile: 188 2631 2629
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Company Info

Foshan Jiazhinuo Biotechnology Co.,Ltd [China (Mainland)]


Business Type:Manufacturer, Trading Company
City: Foshan
Province/State: Guangdong
Country/Region: China (Mainland)

Karry:   skype

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